Related Experiment Video
Updated: Jun 9, 2025
10:43
Rapid and Low-cost Prototyping of Medical Devices Using 3D Printed Molds for Liquid Injection Molding
Published on: June 27, 2014
19.8K
Fabrication of Polypill Pharmaceutical Dosage Forms Using Fused Deposition Modeling 3D Printing: A Systematic Review
Haya Yasin1,2, Moawia M A Al-Tabakha2, Siok Yee Chan1
1School of Pharmaceutical Sciences, Universiti Sains Malaysia, Gelugor 11800, Pulau Pinang, Malaysia.
Pharmaceutics
|October 26, 2024
Summary
Fused Deposition Modeling (FDM) 3D printing shows promise for creating personalized polypills. Addressing challenges like high printing temperatures is key for its pharmaceutical manufacturing potential.
Area of Science:
- Pharmaceutical Technology
- Additive Manufacturing
- Drug Delivery Systems
Background:
- Advancements in patient care and healthcare systems are transforming pharmacy.
- The FDA approval of Spritam (levetiracetam), the first 3D-printed drug, has spurred interest in Fused Deposition Modeling (FDM) 3D printing for pharmaceuticals, especially polypills.
Purpose of the Study:
- To review Fused Deposition Modeling (FDM) 3D printing applications in pharmaceutical dosage form development.
- To explore the potential of FDM 3D printing for creating personalized polypills.
Main Methods:
- Review of 14 studies on FDM 3D-printed polypills from a pool of 60.
- Analysis of FDM operation, printing parameters, materials, additives, advantages, and limitations.
Main Results:
- A growing number of publications indicates increasing global interest in FDM 3D printing for pharmaceuticals.
- The UK leads in research output related to FDM 3D-printed polypills.
Conclusions:
- FDM 3D printing enables personalized medicine through precise control over dosage forms.
- Key challenges include drug stability at high temperatures and the need for standardized Good Manufacturing Practice (GMP) guidelines for large-scale production.
