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Updated: Jun 9, 2025

Quantification of Hydrogen Concentrations in Surface and Interface Layers and Bulk Materials through Depth Profiling with Nuclear Reaction Analysis
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Structural Analysis of Hyaluronic Acid Fillers Using Nuclear Magnetic Resonance: Implications for Quality Control and

Won Lee1, Eun-Jung Yang2

  • 1Yonsei E1 Plastic Surgery Clinic, Anyang 14072, Republic of Korea.

Polymers
|October 26, 2024
PubMed

Keywords:
1,4-butanediol diglycidyl ether (BDDE)hyaluronic acidhyaluronic acid fillernuclear magnetic resonance (NMR)

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Nuclear magnetic resonance (NMR) spectroscopy is a very valuable analytical technique for researchers. It has been used for more than 50 years as an analytical tool. F. Bloch and E. Purcell formulated NMR in 1946 and won the 1952 Nobel Prize in Physics  for their work. Biological macromolecules such as proteins, nucleic acids, lipids, and organic molecules including pharmaceutical compounds, can be studied using this versatile tool that exploits the magnetic properties of certain nuclei.
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