Related Experiment Video

Updated: Jul 28, 2026

In Vivo Inhibition of MicroRNA to Decrease Tumor Growth in Mice
07:02

In Vivo Inhibition of MicroRNA to Decrease Tumor Growth in Mice

Published on: August 23, 2019

Hypothyroidism presenting as growth retardation. A case report

M Chasen, I Cumming, D Wilton

    South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
    |February 1, 1986
    PubMed

    Insights

    Childhood hypothyroidism can cause growth retardation. Early diagnosis and treatment are crucial for normal development and growth, highlighting the need for newborn screening programs.

    Area of Science:

    • Pediatrics
    • Endocrinology
    • Genetics

    Background:

    • Childhood hypothyroidism is a condition affecting growth and development.
    • Early identification is key to preventing long-term health issues.
    • Short stature is a potential, yet often overlooked, symptom in children.

    Observation:

    • This report details an unusual case of hypothyroidism presenting primarily as growth retardation.
    • Clinical features associated with pediatric hypothyroidism were examined.
    • Diagnostic laboratory and specialized investigations were reviewed.

    Findings:

    • Hypothyroidism should be considered in the differential diagnosis of short stature in children.
    • Prompt treatment can lead to normal mental development and physical growth.
    • The case underscores the diagnostic challenges and importance of timely intervention.

    Implications:

    • Emphasizes the critical role of early hypothyroidism detection in pediatric care.
    • Supports the implementation of universal newborn screening for hypothyroidism.
    • Highlights the potential for improved long-term outcomes in affected children through early management.

    More Related Videos

    Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer03:55

    Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

    Published on: June 9, 2023

    Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy03:57

    Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy

    Published on: July 14, 2023

    Related Concept Videos

    Nature and Nurture01:10

    Nature and Nurture

    Many human characteristics, like height, are shaped by both nature—in other words, by our genes—and by nurture, or our environment. For example, chronic stress during childhood inhibits the production of growth hormones and consequently reduces bone growth and height. Scientists estimate that 70-90% of variation in height is due to genetic differences among individuals, and 10-30% of variation in height is due to differences in the environments that individuals experience, such as differences...
    Hormones and Bone Tissue01:17

    Hormones and Bone Tissue

    The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
    Hormones That Influence Osteoblasts and/or Maintain the Matrix
    Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
    Anorexia Nervosa01:28

    Anorexia Nervosa

    Anorexia nervosa is a complex and severe eating disorder characterized by an intense fear of weight gain, an unrelenting pursuit of thinness, and a distorted body image. It often leads to dangerously low body weight relative to an individual's age and height. This disorder is marked by significant physical and psychological consequences, making it one of the most life-threatening psychiatric illnesses.
    Symptoms and Physical Effects
    Individuals with anorexia nervosa commonly exhibit extreme...
    Hyperthyroidism II: Pathophysiology01:27

    Hyperthyroidism II: Pathophysiology

    Hyperthyroidism is a hypermetabolic state caused by elevated levels of thyroid hormones, triiodothyronine (T3) and thyroxine (T4). It results from dysregulation at the thyroid, pituitary, or immune system level and affects multiple organ systems.PathophysiologyThe most common cause of hyperthyroidism is Graves’ disease, an autoimmune disorder in which antibodies, specifically thyroid-stimulating antibodies (TSAb), a subtype of TSH receptor antibodies (TRAb), bind to and activate TSH receptors...
    Graves' Disease I: Introduction01:28

    Graves' Disease I: Introduction

    Graves' disease is an autoimmune disorder that causes hyperthyroidism, or overactivity of the thyroid gland. It results from autoantibodies called thyroid-stimulating immunoglobulins (TSIs), which bind to thyroid-stimulating hormone (TSH) receptors, leading to overstimulation of hormone production and a hypermetabolic state.EtiologyAlthough considered idiopathic, Graves’ disease has well-established contributing factors. There is a strong genetic component, with increased prevalence in...
    Graves Disease II: Pathophysiology01:24

    Graves Disease II: Pathophysiology

    Graves’ disease is an autoimmune disorder characterized by the production of thyroid-stimulating immunoglobulins (TSI) that activate TSH receptors, leading to excessive synthesis and release of thyroid hormones (T3 and T4) and resulting in hyperthyroidism.Among all causes of hyperthyroidism, Graves’ disease is the most common and can happen at any age, though it is more frequent in women. It produces a hypermetabolic state with features such as weight loss, tachycardia, tremor, and heat...