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Updated: Jun 9, 2025

Functional Assessment of Intestinal Tight Junction Barrier and Ion Permeability in Native Tissue by Ussing Chamber Technique
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Tight Junctions and Cancer: Targeting Claudin-1 and Claudin-4 in Thyroid Pathologies

Jędrzej Borowczak1, Dariusz Łaszczych2, Katarzyna Olejnik3

  • 1Department of Clinical Oncology, Oncology Centre Prof. Franciszek Łukaszczyk Memorial Hospital, 85-796 Bydgoszcz, Poland.

Pharmaceuticals (Basel, Switzerland)
|October 26, 2024
PubMed
Summary

Claudin-1 and claudin-4 expression varies in thyroid pathologies. Loss of these tight junction proteins indicates aggressive thyroid cancers, impacting patient prognosis and survival.

Keywords:
claudin-1claudinspathologyprognostic markertargeted therapythyroid cancer

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