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Updated: Jun 9, 2025

A Novel Technique for Generating and Observing Chemiluminescence in a Biological Setting
Published on: March 9, 2017
Recent Advances in Luminophores for Enhanced Electrochemiluminescence Analysis
Zhihan Han1, Hao Ding1, Dechen Jiang1
1State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China.
Abstract:
Electrochemiluminescence (ECL) detection is widely applied in many fields, including chemical measurement, biological analysis, and clinic tests, due to its high sensitivity. Currently, the fast development of many new electrochemical luminophores is continuously improving the ECL-based detection ability. Besides the enhancement of luminescence emission for a high detection sensitivity, minimizing the effect of co-reactants on ECL detection and achieving multiple analysis in one sample are also the main directions in this field. This review focuses on a summary of recently prepared new luminophores to achieve the three aims mentioned above. Especially, the review is composed by three parts, focusing on the luminophores or materials with high ECL efficiency, self-enhancing properties, and multi-color ECL luminophores. The fabrication of biosensors using these molecules is also reviewed to exhibit the advances in biological applications.
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