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Published on: March 12, 2019
Factors Associated with Postoperative Complications After Congenital Duodenal Obstruction Surgery: A Retrospective
Andreea Moga1,2, Radu Bălănescu1,2, Laura Bălănescu1,2
1Department of Pediatric Surgery, "Grigore Alexandrescu" Clinical Emergency Hospital for Children, 011743 Bucharest, Romania.
Insights
Infants with congenital duodenal obstruction and low Apgar scores (below 8) or neurological/pulmonary issues face higher complication risks. Other anomalies and birth weight are not predictive factors for these outcomes.
Area of Science:
- Pediatric Surgery
- Gastrointestinal Surgery
- Neonatal Care
Background:
- Duodenal atresia and stenosis are primary causes of intestinal obstruction in infants.
- Associated anomalies and postoperative complications significantly affect survival rates in affected children.
Purpose of the Study:
- To analyze the impact of associated congenital anomalies and clinical factors on postoperative complications in infants with congenital duodenal obstruction.
- To identify prognostic factors influencing outcomes in pediatric patients with duodenal obstruction.
Main Methods:
- Retrospective analysis of 74 infants and children treated for congenital duodenal obstruction between January 2010 and August 2023.
- Data collected included congenital anomalies, Apgar scores, birth weights, surgical techniques, and types of postoperative complications.
Main Results:
- Associated anomalies were frequent, including cardiac (33), Down syndrome (13), and neurological (11).
- Early (21) and late (6) postoperative complications occurred, with sepsis (7) and adhesive bowel obstruction (7) being notable.
- An Apgar score below 8, and neurological and pulmonary abnormalities were surprisingly linked to increased postoperative complications.
Conclusions:
- Low Apgar scores and specific comorbidities like neurological and pulmonary issues are risk factors for complications after surgery for congenital duodenal obstruction.
- Factors such as other congenital anomalies, low birth weight, and age at admission were not found to be significant prognostic indicators.
Abstract:
Background and Objectives: Duodenal atresia and stenosis are common causes of intestinal obstruction. Associated anomalies significantly influence early postoperative mortality, while postoperative complications impact long-term survival. Materials and Methods: Over a 13-year period from January 2010 to August 2023, a total of 74 infants and children with congenital duodenal obstruction were treated at "Grigore Alexandrescu" Children's Emergency Hospital and met the inclusion criteria. All patients diagnosed with duodenal obstruction (both instrinsic and extrinsic causes) were included. Analysed data included congenital anomalies, Apgar scores, birth weights, surgical techniques, and complications. Results: The associated anomalies included cardiac (n = 33), Down syndrome (n = 13), neurological (n = 11), pulmonary (n = 7), renal (n = 4), skeletal (n = 1), and gastrointestinal and hepatobiliopancreatic anomalies (n = 25). In total, 12 patients experienced perioperative ventilation problems. Early postoperative complications (within 30 days) occurred in 21 patients, while 6 had late postoperative complications (after 30 days). Among non-surgical complications, we noted ventilation problems, sepsis (n = 7), and pneumothorax (n = 1). Surgical complications included adhesive bowel obstruction (n = 7), incisional hernia (n = 3), peritonitis (n = 3), dysfunctional duodenoduodenostomy or duodenojejunostomy (n = 3), pneumoperitoneum (n = 5), enteric fistula (n = 3), and volvulus (n = 4). Conclusions: Surprisingly, this retrospective study revealed that an Apgar score below 8, along with neurological and pulmonary abnormalities, is associated with postoperative complications. Conversely, other congenital anomalies, low birth weight, and age at admission do not serve as prognostic factors.
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