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Related Experiment Video

Updated: Jun 9, 2025

Novel Methods for Intranasal Administration Under Inhalation Anesthesia to Evaluate Nose-to-Brain Drug Delivery

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Minimizing Narcotic Use in Rhinoplasty: An Updated Narrative Review and Protocol.

Madison Mai-Lan Cheung¹, Anil Shah^2,3

¹College of Medicine at Rockford, University of Illinois Chicago, Rockford, IL 61107, USA.

Life (Basel, Switzerland)

|October 26, 2024

Summary

This study details an opioid-sparing protocol for rhinoplasty, combining acetaminophen, celecoxib, gabapentin, dexmedetomidine, lidocaine, and bupivacaine to minimize opioid use and enhance pain management.

Keywords:

analgesia anesthesia opioid usage opioid-sparing pain management postoperative pain rhinoplasty

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Area of Science:

Anesthesiology
Plastic Surgery
Pain Management

Background:

Opioid analgesics are standard for post-surgical pain but carry risks like addiction.
Reducing opioid consumption in surgery is a growing trend, yet specific protocols for rhinoplasty are evolving.
This paper refines an existing opioid-sparing protocol for rhinoplasty using updated evidence.

Purpose of the Study:

To develop and detail an evidence-based, opioid-sparing pain management protocol for rhinoplasty.
To summarize effective analgesic agents for reducing opioid requirements in surgical pain.
To provide a structured protocol based on optimal timing of analgesic administration.

Main Methods:

Literature review of PubMed using terms like "rhinoplasty" and "opioid sparing".
Identification and summarization of analgesic agents with opioid-reducing potential.
Compilation of a multimodal pain management protocol based on preoperative, intraoperative, and postoperative administration.

Main Results:

Recommended preoperative agents: oral acetaminophen, celecoxib, and gabapentin.
Recommended intraoperative agents: intravenous dexmedetomidine, lidocaine, and bupivacaine nerve blocks.
Recommended postoperative agents: oral acetaminophen and celecoxib.

Conclusions:

A multimodal analgesic approach can effectively reduce opioid use in rhinoplasty.
Careful selection of agents considering side effects and contraindications is crucial.
The proposed protocol offers a structured framework for opioid-sparing pain management in rhinoplasty.