Bioactive Self-Polymerizing Resin with Surface Pre-Reacted Glass Ionomer Fillers for Suppressed Enamel...

Area of Science:

• Biomaterials Science
• Dental Materials
• Restorative Dentistry

Background:

• Dental enamel repair research focuses on bioactive and biomimetic materials.
• Artificial materials and pseudo-enamel are explored for damaged enamel surfaces.

Purpose of the Study:

• To develop a bioactive auto-polymerizing resin (APR) incorporating surface-pre-reacted glass ionomer (S-PRG) fillers.
• To evaluate the bioactive effects of the S-PRG-modified APR, including pH neutralization, ion release, and inhibition of enamel demineralization.

Main Methods:

• Prepared APR with varying S-PRG filler quantities.
• Assessed pH neutralization and ion release using ion-specific electrodes and ICP-AES.
• Examined enamel demineralization inhibition using scanning electron microscopy (SEM) after 7 days of incubation.

Main Results:

• APR with S-PRG filler neutralized lactic acid (pH 4.0) immediately via ion release.
• Strontium (Sr) ion release peaked on day one; other ions released in the order F > B > Si > Al > Na, decreasing weekly.
• SEM revealed no enamel demineralization with S-PRG containing APR, unlike control groups.

Conclusions:

• APR containing S-PRG fillers exhibits acid buffering capacity.
• The material demonstrates bioactive properties by suppressing enamel demineralization.
• S-PRG modified APR shows potential for treating damaged dental enamel.