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Embedded IoT Design for Bioreactor Sensor Integration.

Laurentiu Marius Baicu1, Mihaela Andrei1, George Adrian Ifrim2

  • 1Electronics and Telecommunications Department, "Dunarea de Jos" University of Galati, 800008 Galati, Romania.

Sensors (Basel, Switzerland)
|October 26, 2024
PubMed
Summary

This study introduces an Internet of Things (IoT) system for bioreactor control, enhancing cell cultivation with precise temperature and turbidity management. The system improves bioprocessing efficiency and reliability through real-time monitoring and cloud data transmission.

Keywords:
ESPIoTPeltier modulebioreactorembeddedturbidity

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Area of Science:

  • Biotechnology
  • Environmental Monitoring
  • Embedded Systems

Background:

  • Traditional bioreactor control systems often lack real-time, integrated monitoring capabilities.
  • Optimizing cell cultivation requires precise control over environmental parameters like temperature and turbidity.
  • Advancements in IoT technology offer potential for enhanced bioprocessing efficiency.

Purpose of the Study:

  • To develop and evaluate an embedded Internet of Things (IoT) system for integrated bioreactor sensor monitoring.
  • To optimize temperature and turbidity control during cell cultivation processes.
  • To demonstrate the system's effectiveness in improving bioprocessing efficiency and reliability.

Main Methods:

  • An embedded IoT system was designed using an ESP32 development board.
  • Key components included DS18B20 temperature and TS-300B turbidity sensors, and a Peltier module for temperature regulation.
  • Real-time data was transmitted to cloud platforms for advanced process control.

Main Results:

  • The system demonstrated superior analog-to-digital conversion and dual-core processing capabilities.
  • Experimental results on yeast cultures confirmed effective maintenance of optimal growth conditions.
  • The system successfully facilitated real-time monitoring and data transmission for enhanced process control.

Conclusions:

  • The proposed embedded IoT system offers a reliable and efficient solution for bioreactor sensor integration.
  • This technology has the potential to significantly enhance bioprocessing techniques and culture cultivation.
  • The study highlights the practical application of IoT in optimizing bioreactor environments for improved outcomes.