Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A progressive spinal myelinopathy in beef cattle.

R B Richards, J R Edwards

    Veterinary Pathology
    |January 1, 1986
    PubMed
    Summary

    Hind limb ataxia in Murray Grey calves is linked to spinal cord myelin degeneration. This condition affects the central nervous system, causing progressive myelin loss and neurological deficits.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Development of ISB 1442, a CD38 and CD47 bispecific biparatopic antibody innate cell modulator for the treatment of multiple myeloma.

    Nature communications·2024
    Same author

    Image-Guided Transvaginal and Transabdominal Drain Placement for Surgical Navigation in a Patient with Tubo-Ovarian Abscess and Obstructed Hemivagina and Ipsilateral Renal Anomaly Syndrome.

    Journal of pediatric and adolescent gynecology·2021
    Same author

    CONGENITAL PROGRESSIVE OVINE MUSCULAR DYSTROPHY IN WESTERN AUSTRALIA.

    Australian veterinary journal·2017
    Same author

    A loss of host-derived MMP-7 promotes myeloma growth and osteolytic bone disease in vivo.

    Molecular cancer·2017
    Same author

    Epigenetic activation of the prostaglandin receptor EP4 promotes resistance to endocrine therapy for breast cancer.

    Oncogene·2016
    Same author

    Persistence of Influenza A (H1N1) Virus on Stainless Steel Surfaces.

    Applied and environmental microbiology·2016

    Area of Science:

    • Veterinary Neurology
    • Comparative Pathology
    • Animal Science

    Background:

    • Ataxia is a common neurological sign in young cattle.
    • Enzootic ataxia in red deer shares similarities with observed calf conditions.
    • Murray Grey calves are disproportionately affected.

    Purpose of the Study:

    • To investigate the cause of hind limb ataxia in nine calves.
    • To characterize the neuropathological findings in affected animals.
    • To compare the condition with enzootic ataxia in red deer.

    Main Methods:

    • Clinical examination of affected calves.
    • Necropsy and histopathological examination of central nervous system tissues.
    • Microscopic evaluation of spinal cord, brainstem, and cerebellum.

    Main Results:

    • Degenerative lesions in spinal white matter were identified.
    • Neuronal chromatolysis was observed in the red nucleus, spinal grey matter, medulla oblongata, and cerebellum.
    • Clinical signs and lesions mimicked enzootic ataxia of red deer.

    Conclusions:

    • The condition in calves is characterized by primary central nervous system myelin defects.
    • Progressive myelin loss, particularly in the spinal cord, is the likely cause of ataxia.
    • This suggests a potential breed-specific susceptibility in Murray Grey calves.

    Related Experiment Videos