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Anomaly detection scheme for lung CT images using vector quantized variational auto-encoder with support vector data

Zhihui Gao1, Ryohei Nakayama2, Akiyoshi Hizukuri1

  • 1Graduate School of Science and Engineering, Ritsumeikan University, 1-1-1 Noji-Higashi, Kusatsu, Shiga, 525-8577, Japan.

Radiological Physics and Technology
|October 26, 2024
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Summary
This summary is machine-generated.

This study introduces a Vector Quantized-Variational Auto-Encoder with Support Vector Data Description (VQ-VAE with SVDD) for detecting lung lesions in CT images. This novel anomaly detection scheme improves accuracy over conventional methods, aiding in faster screening.

Keywords:
Anomaly detectionLung CT imagesSVDDVQ-VAE

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Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Computer Vision

Background:

  • Lung CT image analysis is crucial for disease detection.
  • Accurate anomaly detection in medical images remains a challenge.
  • Automated systems can assist radiologists in screening.

Purpose of the Study:

  • To develop an advanced anomaly-detection scheme for lung lesions in CT images.
  • To enhance the accuracy of lesion identification using deep learning.
  • To reduce interpretation time in CT screening processes.

Main Methods:

  • Implementation of a Vector Quantized-Variational Auto-Encoder (VQ-VAE) integrated with Support Vector Data Description (SVDD).
  • VQ-VAE with SVDD utilizes two encoders and two decoders for latent variable mapping and image reconstruction.
  • Anomaly score calculation based on image reconstruction error and latent variable distance from a hypersphere center.

Main Results:

  • The VQ-VAE with SVDD achieved an area under the ROC curve of 0.76.
  • This represents a significant improvement compared to the conventional VAE, which achieved 0.63 (p < .001).
  • The proposed method demonstrates higher anomaly detection accuracy.

Conclusions:

  • VQ-VAE with SVDD offers superior performance for anomaly detection in lung CT images.
  • The developed method can effectively identify examinees with lesions.
  • This approach is expected to reduce interpretation time for CT screening.