Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

89
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
89

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Patient stratification for dose scaling in cervical cancer: a model-based analysis using image-guided adaptive brachytherapy.

Journal of radiation research·2026
Same author

Prospective evaluation of oxygen saturation endoscopic imaging for radiotherapy response in head and neck cancer.

Communications medicine·2026
Same author

In vivo dosimetry of cardiac implantable electronic devices with a radiophotoluminescent glass dosimeter in patients undergoing radiotherapy.

Radiological physics and technology·2026
Same author

Cross-anatomical evaluation of a deep-learning auto-contouring system: qualitative, geometric, and dosimetric validation.

Journal of applied clinical medical physics·2026
Same author

Minimization of Geometric Uncertainties and Setup Errors Improves Tumor Control for Intracranial Stereotactic Radiosurgery.

Advances in radiation oncology·2026
Same author

Evaluation of segmentation accuracy and the improvement of time effectiveness using deep learning-based segmentation in <sup>177</sup>Lu-DOTATATE dosimetry.

EJNMMI physics·2026

Related Experiment Video

Updated: Jun 9, 2025

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
09:49

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods

Published on: April 24, 2020

9.9K

Three-dimensional source position verification in image-guided high-dose-rate brachytherapy using an XCT-based gel

Miki Yonemura1, Hidenobu Tachibana1, Toru Kojima2

  • 1Radiation Safety and Quality Assurance Division, National Cancer Center Hospital East, Chiba, Japan.

Medical Physics
|October 26, 2024
PubMed
Summary

This study introduces an X-ray computed tomography (XCT)-based gel dosimeter for efficient quality assurance in image-guided brachytherapy (IGBT). The novel dosimeter accurately verifies 3D source dwell positions, enhancing treatment workflow precision.

Keywords:
brachytherapyend‐to‐end processpolymer gel dosimeter

More Related Videos

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
08:17

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

15.7K
Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy
11:38

Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy

Published on: July 3, 2014

46.7K

Related Experiment Videos

Last Updated: Jun 9, 2025

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
09:49

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods

Published on: April 24, 2020

9.9K
Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
08:17

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

15.7K
Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy
11:38

Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy

Published on: July 3, 2014

46.7K

Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Dosimetry

Background:

  • Comprehensive quality assurance (QA) for high-dose-rate brachytherapy (HDR-BT) workflows, including imaging, planning, and irradiation, is often lacking.
  • Current QA for source dwell position verification is typically limited to one or two dimensions.
  • Magnetic resonance imaging (MRI)-based gel dosimetry is effective for 3D dose verification in image-guided brachytherapy (IGBT), but MRI scanners are not universally accessible and scanning is time-consuming.

Purpose of the Study:

  • To design and develop an efficient X-ray computed tomography (XCT)-based polymer gel dosimeter for QA.
  • To enable a seamless workflow for image-guided brachytherapy (IGBT) using a novel gel dosimeter compatible with XCT.

Main Methods:

  • A modified polymer gel dosimeter was developed for direct insertion of brachytherapy applicators.
  • The gel dosimeter was evaluated for reproducibility of source dwell positions, detectability of positional errors, effect of transfer tube looping, inter-observer variation, and gel robustness.
  • Source dwell positions were determined using XCT by analyzing irradiated volumes in pre- and post-irradiation images, and compared with planned positions.

Main Results:

  • The developed gel dosimeter exhibited 1250% greater hardness than previous formulations.
  • QA testing, including CT acquisition, planning, irradiation, and analysis, was completed in approximately one hour.
  • Source dwell position verification demonstrated high precision, with average displacements within 0.5 mm for reproducibility and < 1 mm for detecting introduced errors (except along the source path), and minimal inter-observer variation (< 0.57 mm).

Conclusions:

  • The XCT-based gel dosimeter provides a precise and efficient method for verifying 3D source dwell positions in IGBT.
  • This technology facilitates a seamless QA workflow for image-guided brachytherapy, improving treatment accuracy and efficiency.