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Related Experiment Video

Updated: Jun 9, 2025

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Co-developing frameworks towards environmentally directed pharmaceutical prescribing in Scotland - A mixed methods

Lydia Niemi1, Naoko Arakawa2, Miriam Glendell3

  • 1Environmental Research Institute, University of the Highlands and Islands, UK.

The Science of the Total Environment
|October 26, 2024
PubMed
Summary
This summary is machine-generated.

Pharmaceuticals in water pose a public health risk. This study developed a framework to assess pharmaceutical pollution, identifying clarithromycin as a high-risk pollutant in Scottish freshwater catchments.

Keywords:
Catchment modelling and mappingConsensus developmentEnvironmental risk assessmentMulti-criteria decision-makingPharmaceutical pollutionPublic health

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Area of Science:

  • Environmental Science
  • Public Health
  • Health Services Research

Background:

  • Pharmaceuticals in aquatic environments are a global concern.
  • Scottish healthcare aims to reduce environmental impact from medicine use.
  • A knowledge support tool is needed for healthcare professionals regarding pharmaceutical pollution.

Purpose of the Study:

  • Develop a framework to assess the environmental impact of pharmaceuticals.
  • Create a knowledge support tool for healthcare professionals.
  • Focus on pharmaceutical pollution in freshwater catchments.

Main Methods:

  • Nominal Group Technique used for stakeholder consensus on pharmaceuticals and model factors.
  • Bayesian Belief Network modelling to predict environmental impact (hazard and exposure).
  • Scotland-wide mapping of pharmaceutical pollution risk in freshwater catchments.

Main Results:

  • Model calculated pollution risk scores for individual pharmaceuticals.
  • Clarithromycin showed the highest risk, exceeding predicted no-effect concentrations in most modelled catchments (>80% probability in 35/40).
  • Model generally overpredicted risk compared to observed data, indicating a need for refined factors and data resolution.

Conclusions:

  • A novel trans-disciplinary approach was demonstrated for integrating environmental information into healthcare decision-making.
  • The developed framework aids in understanding and managing pharmaceutical pollution.
  • Future work will refine the model and develop electronic interfaces for healthcare professionals.