Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Effects of EDTA on End-Point Detection Methods01:18

Effects of EDTA on End-Point Detection Methods

259
Different methods, such as visual observance of metal-ion indicators, spectroscopic techniques, and potentiometric methods, can determine the endpoint of an EDTA titration.
In the visual method, metal-ion indicators (metallochromic dyes), which have distinct colors in their free and complex forms, are added to the mixture to signal the titration's end point. They form stable complexes with metal ions, but these complexes are weaker than the corresponding metal–EDTA complexes. As a...
259
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

134
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
134
Acute Coronary Syndrome III: Diagnostic studies01:30

Acute Coronary Syndrome III: Diagnostic studies

3
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
3
Dysrhythmias V: Evaluating Dysrhythmias01:30

Dysrhythmias V: Evaluating Dysrhythmias

3
Dysrhythmias, also known as arrhythmias, are disturbances in the heart's rhythm that range from benign to life-threatening. A thorough evaluation is crucial for appropriate management and involves a comprehensive medical history, physical examination, and various diagnostic tests.Medical HistorySymptoms: Collect detailed information on palpitations, dizziness, syncope, chest pain, and fatigue. Note their onset, frequency, and triggers.Previous Cardiac Issues: Document any history of heart...
3
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

86
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
86
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

7
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
7

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cardiac Implantable Electronic Devices Remote Programming.

Circulation. Arrhythmia and electrophysiology·2026
Same author

Early complications and long-term outcome of patients treated with a Subcutaneous Cardioverter-Defibrillator: temporal trends and clinical implications of the anesthetic strategies adopted at implant.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology·2026
Same author

One-Year Outcomes of the First 1000 Patients Implanted With the Medtronic Micra AV Leadless Pacing System in France: The AV-CESAR Cohort Study.

Circulation. Arrhythmia and electrophysiology·2026
Same author

PASTEC: an open clinical infrastructure for data aggregation and prospective validation of AI in cardiac remote monitoring.

NPJ digital medicine·2026
Same author

A Multi-Center Trained Residual Neural Network for Robust Classification of Atrial High-Rate Episodes in Remotely Monitored Pacemakers and Defibrillators.

Sensors (Basel, Switzerland)·2026
Same author

The role of His-Purkinje system activation in preventing malignant reentrant ventricular arrhythmias during left bundle branch area pacing: Reverse electrical remodeling or restored left ventricular activation?

Heart rhythm·2026

Related Experiment Video

Updated: Jun 9, 2025

Author Spotlight: Enhancing Diagnostic Strategies and Biomarker Development for Comprehensive Lung Function Analysis
05:56

Author Spotlight: Enhancing Diagnostic Strategies and Biomarker Development for Comprehensive Lung Function Analysis

Published on: August 9, 2024

1.1K

Diagnostic Approach to Suspected Lead Failure.

Anand Thiyagarajah1, Marc Strik2, Sylvain Ploux2

  • 1Department of Cardiology, University of Adelaide and Royal Adelaide Hospital, Port Road, Adelaide, SA 5000, Australia; CHU de Bordeaux, service de Cardiologie-électrophysiologie et stimulation cardiaque, INSERM, U 1045, Bordeaux F-33000, France; Department of Cardiology-Electrophysiology and Cardiac Pacing, Univ. Bordeaux, INSERM, CRCTB, U 1045, IHU Liryc, Bordeaux F-33000, France.

Cardiac Electrophysiology Clinics
|October 26, 2024
PubMed
Summary

Transvenous lead failure in cardiac pacing affects 1-2% of patients. Early detection using device algorithms and remote monitoring can prevent complications like pacing inhibition and inappropriate shocks.

Keywords:
ICDLeadOversensingPacingRemote monitoring

More Related Videos

Handheld Metal Detector Screening for Metallic Foreign Body Ingestion in Children
04:55

Handheld Metal Detector Screening for Metallic Foreign Body Ingestion in Children

Published on: September 11, 2018

10.8K
Assessing Iron Deposition in the Brains of 5xFAD Mice by Perls'/DAB Staining
07:32

Assessing Iron Deposition in the Brains of 5xFAD Mice by Perls'/DAB Staining

Published on: May 23, 2025

68

Related Experiment Videos

Last Updated: Jun 9, 2025

Author Spotlight: Enhancing Diagnostic Strategies and Biomarker Development for Comprehensive Lung Function Analysis
05:56

Author Spotlight: Enhancing Diagnostic Strategies and Biomarker Development for Comprehensive Lung Function Analysis

Published on: August 9, 2024

1.1K
Handheld Metal Detector Screening for Metallic Foreign Body Ingestion in Children
04:55

Handheld Metal Detector Screening for Metallic Foreign Body Ingestion in Children

Published on: September 11, 2018

10.8K
Assessing Iron Deposition in the Brains of 5xFAD Mice by Perls'/DAB Staining
07:32

Assessing Iron Deposition in the Brains of 5xFAD Mice by Perls'/DAB Staining

Published on: May 23, 2025

68

Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Medical Device Technology

Background:

  • Transvenous lead failure is a significant clinical issue in cardiac pacing and defibrillation, occurring in 1-2% of patients.
  • Oversensing of non-physiological signals often precedes lead impedance changes, potentially causing pacing inhibition or inappropriate shocks.
  • Current management strategies necessitate timely diagnosis to prevent adverse patient outcomes.

Purpose of the Study:

  • To review the mechanisms underlying transvenous lead failure.
  • To propose a diagnostic approach for identifying suspected lead failure.
  • To emphasize the role of device algorithms and remote monitoring in early detection and management.

Main Methods:

  • Literature review of mechanisms of transvenous lead failure.
  • Analysis of the relationship between oversensing, lead impedance, and clinical complications.
  • Discussion of device-based algorithms for signal detection.
  • Integration of remote monitoring concepts for proactive management.

Main Results:

  • Lead failure can manifest through oversensing, leading to critical device malfunctions.
  • Device algorithms can identify abnormal signals indicative of lead issues.
  • Remote monitoring facilitates timely intervention for lead failure.

Conclusions:

  • Early diagnosis and management of transvenous lead failure are crucial for patient safety.
  • Device algorithms combined with remote monitoring offer a promising strategy for proactive lead failure detection.
  • A structured diagnostic approach can improve the management of patients with suspected lead failure.