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Published on: January 27, 2023
Continuous-wave Doppler in children with ventricular septal defect: noninvasive estimation of interventricular
Insights
Continuous-wave Doppler accurately estimates ventricular septal defect (VSD) pressure gradients in children. This noninvasive method aids in assessing right ventricular pressure and distinguishing VSD types.
Area of Science:
- Pediatric Cardiology
- Echocardiography
- Congenital Heart Disease
Background:
- Ventricular septal defect (VSD) is a common congenital heart anomaly.
- Accurate pressure gradient estimation is crucial for VSD management.
- Noninvasive methods are preferred for pediatric cardiac assessment.
Purpose of the Study:
- To evaluate the accuracy of continuous-wave Doppler in estimating the pressure gradient across VSDs in children.
- To compare Doppler-derived gradients with catheterization measurements.
- To assess the utility of Doppler in estimating right ventricular and pulmonary artery pressures.
Main Methods:
- Continuous-wave Doppler echocardiography was performed in 28 children with VSD.
- Maximal velocity was measured during cardiac catheterization.
- Doppler-predicted gradients were compared with simultaneously measured catheterization gradients.
Main Results:
- Doppler gradients (10-71 mm Hg) showed excellent correlation with catheterization gradients (r=0.97, p>=0.001).
- In isolated VSD, Doppler accurately estimated right ventricular pressure (r=0.93).
- An inverse correlation was found between pulmonary-to-systemic resistance ratio and maximal velocity (r=-0.77).
Conclusions:
- Continuous-wave Doppler is a precise, noninvasive tool for measuring instantaneous VSD pressure gradients in children.
- It enables accurate estimation of right ventricular and pulmonary artery pressures in isolated VSD.
- This method can differentiate between restrictive and nonrestrictive VSDs.
Abstract:
Continuous-wave Doppler was used to estimate the pressure gradient between the right and left ventricles in 28 children with ventricular septal defect (VSD). Doppler measurement of maximal velocity was performed during cardiac catheterization and the Doppler-predicted gradient was compared with the peak-to-peak gradient measured simultaneously by catheter. Doppler gradients ranged from 10 to 71 mm Hg and correlated well with measured gradient (r = 0.97, p greater than or equal to 0.001). Fourteen patients had isolated VSD, and in these patients Doppler measurements of gradient allowed accurate estimation of right ventricular pressure (r = 0.93). There was an inverse correlation between the ratio of pulmonary to systemic resistance and maximal velocity (r = -0.77). Thus, continuous-wave Doppler is an accurate means of measuring instantaneous VSD pressure gradient in children with congenital heart disease and can be used to estimate the right ventricular and pulmonary artery pressure in children with isolated VSD. This noninvasive method can be used to distinguish restrictive from nonrestrictive VSD.
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