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Updated: Jun 9, 2025

Machine Learning Algorithms for Early Detection of Bone Metastases in an Experimental Rat Model
Published on: August 16, 2020
Machine learning algorithms translate big data into predictive breeding accuracy
José Crossa1, Osval A Montesinos-Lopez2, Germano Costa-Neto3
1Louisiana State University, College of Agriculture, Baton Rouge, LA, USA; Colegio de Postgraduados, Montecillos, CP 56230, Estado de México, Mexico; International Maize and Wheat Improvement Center (CIMMYT), Carretera México- Veracruz Km 45, El Batán, Texcoco, CP 56237, Estado de México, Mexico; Department of Statistics and Operations Research and Distinguished Scientist Fellowship Program, King Saud University, Riyadh 11451, Saudi Arabia.
Abstract:
Statistical machine learning (ML) extracts patterns from extensive genomic, phenotypic, and environmental data. ML algorithms automatically identify relevant features and use cross-validation to ensure robust models and improve prediction reliability in new lines. Furthermore, ML analyses of genotype-by-environment (G×E) interactions can offer insights into the genetic factors that affect performance in specific environments. By leveraging historical breeding data, ML streamlines strategies and automates analyses to reveal genomic patterns. In this review we examine the transformative impact of big data, including multi-trait genomics, phenomics, and environmental covariables, on genomic-enabled prediction in plant breeding. We discuss how big data and ML are revolutionizing the field by enhancing prediction accuracy, deepening our understanding of G×E interactions, and optimizing breeding strategies through the analysis of extensive and diverse datasets.
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