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COVID-19 and Good's Syndrome After Thymectomy
Ingyin May1, Srikanth Akunuri1
1General Medicine, King's College Hospital NHS Foundation Trust, London, GBR.
Abstract:
Good's syndrome is a rare secondary immunodeficiency characterised by recurrent infection and hypogammaglobulinemia associated with thymus tumour, and symptoms of recurrent infection may persist even after thymectomy. It is characterised by increased susceptibility to bacterial, viral, and fungal infections, as well as autoimmunity. Immunoglobulin replacement therapy has been reported to decrease infection rate, hospitalization, and the rate of antibiotic use in these patients. There are very few reported cases of patients with COVID-19 infection and Good's syndrome; however, there is no strong association proven between these two situations. The patient we report in this article had a COVID-19 infection first, was incidentally diagnosed with thymoma, and got the symptoms of Good's syndrome after thymectomy.
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