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Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
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Combination Therapies and Personalized Medicine02:50

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Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
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Cancer Therapies02:49

Cancer Therapies

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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
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Related Experiment Video

Updated: Jun 9, 2025

Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model
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Parallel Battles: Managing Synchronous Cervical and Triple-Negative Breast Cancers.

Fadila Kouhen1, Malak Chahid1, Reyzane El Mjabber1

  • 1Radiotherapy, International University Hospital Sheikh Khalifa, Mohammed VI University of Sciences and Health (UM6SS), Casablanca, MAR.

Cureus
|October 28, 2024
PubMed
Summary

Managing synchronous triple-negative breast cancer (TNBC) and cervical cancer is complex. This case shows successful treatment with neoadjuvant chemotherapy, surgery, and concurrent chemoradiotherapy, leading to complete pathological response and no recurrence.

Area of Science:

  • Oncology
  • Gynecologic Oncology
  • Breast Oncology

Background:

  • Multiple primary malignancies (MPMs) pose significant diagnostic and therapeutic challenges due to their rarity and unique treatment requirements.
Keywords:
breast cancercervical cancerindividualized treatmentmultidisciplinary approachmultiple primary malignancies

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  • Synchronous triple-negative breast cancer (TNBC) and cervical cancer represent an uncommon and complex clinical scenario.