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Related Experiment Video

Updated: May 17, 2026

Two Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation

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Published on: March 14, 2017

Tertiary Hyperparathyroidism: A Case Report.

Carolina Fernandes¹, Vera Vieira², Cláudia Diogo¹

¹Internal Medicine Department, Unidade Local de Saúde da Região de Leiria, Leiria, PRT.

|October 28, 2024

Summary

This summary is machine-generated.

Tertiary hyperparathyroidism, a condition of excess parathyroid hormone, can arise from prolonged secondary hyperparathyroidism. This case highlights its link to gastrointestinal malabsorption and pathological fractures.

Keywords:

adenoma bariatric surgery hypercalcemia malabsorption tertiary hyperparathyroidism

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Area of Science:

Endocrinology
Nephrology
Gastroenterology

Background:

Tertiary hyperparathyroidism involves autonomous parathyroid hormone secretion, often following prolonged secondary hyperparathyroidism.
It is frequently linked to chronic conditions like chronic kidney disease, renal transplantation, and gastrointestinal malabsorption.

Observation:

A 50-year-old female presented with a pathological fracture of a dorsal vertebra.
Her medical history included biliopancreatic diversion surgery, renal lithiasis with recurrent obstructive pyelonephritis, and limited mobility.

Findings:

The patient's presentation was attributed to tertiary hyperparathyroidism.
This was a consequence of long-term gastrointestinal malabsorption stemming from her prior surgery.

Implications:

This case underscores the importance of recognizing tertiary hyperparathyroidism in patients with a history of gastrointestinal malabsorption.
Early diagnosis and management are crucial to prevent complications such as pathological fractures.