Jove
Visualize
Contact Us

Related Concept Videos

Accessory Structures of the Eye01:17

Accessory Structures of the Eye

1.5K
Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
1.5K
Anatomy of the Eyeball01:20

Anatomy of the Eyeball

6.0K
The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle...
6.0K
Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

4.6K
Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
4.6K
Muscles of the Eye01:20

Muscles of the Eye

1.1K
The muscles of the eye are sophisticated structures that control eye movement and focus, allowing for the precise and rapid adjustments necessary for vision. The human eye is controlled by ten muscles — six extraocular muscles, three intraocular muscles, and one primary eyelid retractor muscle.
Extraocular Muscles
The six extraocular muscles surround the eyeball and control its movements. They are responsible for a wide range of eye motions, including looking up, down, left, right, and...
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Noradrenaline for progressive supranuclear palsy syndromes (NORAPS): a randomised, double-blind, placebo-controlled, crossover Phase IIb clinical trial evaluating the efficacy and safety of oral atomoxetine for treating cognitive and behavioural changes in people with progressive supranuclear palsy syndromes in the UK.

BMJ open·2025
Same author

Pathway to Regulatory Approval of Digital Health Technologies in Progressive Supranuclear Palsy: A Scoping Review.

Brain sciences·2025
Same author

Three decades of the LATER model.

Journal of neurophysiology·2025
Same author

Predicting future fallers in Parkinson's disease using kinematic data over a period of 5 years.

NPJ digital medicine·2024
Same author

Accelerating Parkinson's Disease drug development with federated learning approaches.

NPJ Parkinson's disease·2024
Same author

Daily steps are a predictor of, but perhaps not a modifiable risk factor for Parkinson's Disease: findings from the UK Biobank.

medRxiv : the preprint server for health sciences·2024
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 9, 2025

VisualEyes: A Modular Software System for Oculomotor Experimentation
10:41

VisualEyes: A Modular Software System for Oculomotor Experimentation

Published on: March 25, 2011

12.7K

The oculomotor microcosm.

Chrystalina A Antoniades1

  • 1Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, OX3 9DU, UK.

Brain Communications
|October 28, 2024
PubMed
Summary
This summary is machine-generated.

This study discusses how noradrenergic system changes affect eye movements in Parkinson's disease. Understanding these links is crucial for developing better treatments for the condition.

More Related Videos

Author Spotlight: An Accurate and Quantitative Approach to Study Visual Feature Selectivity of the Optokinetic Reflex in Mice
09:28

Author Spotlight: An Accurate and Quantitative Approach to Study Visual Feature Selectivity of the Optokinetic Reflex in Mice

Published on: June 23, 2023

2.5K
Video-oculography in Mice
09:43

Video-oculography in Mice

Published on: July 19, 2012

23.7K

Related Experiment Videos

Last Updated: Jun 9, 2025

VisualEyes: A Modular Software System for Oculomotor Experimentation
10:41

VisualEyes: A Modular Software System for Oculomotor Experimentation

Published on: March 25, 2011

12.7K
Author Spotlight: An Accurate and Quantitative Approach to Study Visual Feature Selectivity of the Optokinetic Reflex in Mice
09:28

Author Spotlight: An Accurate and Quantitative Approach to Study Visual Feature Selectivity of the Optokinetic Reflex in Mice

Published on: June 23, 2023

2.5K
Video-oculography in Mice
09:43

Video-oculography in Mice

Published on: July 19, 2012

23.7K

Area of Science:

  • Neuroscience
  • Ophthalmology
  • Neurology

Background:

  • Parkinson's disease (PD) is a neurodegenerative disorder affecting motor control.
  • Saccadic eye movements are often impaired in individuals with PD.
  • The noradrenergic system plays a role in regulating various brain functions, including motor control and attention.

Purpose of the Study:

  • To comment on the findings by Orlando et al. regarding noradrenergic modulation of saccades in Parkinson's disease.
  • To highlight the significance of the noradrenergic system in understanding saccade abnormalities in PD.
  • To discuss potential therapeutic implications of targeting the noradrenergic system for PD-related eye movement deficits.

Main Methods:

  • This is a scientific commentary, not an original research study.
  • It analyzes and discusses the findings presented in the referenced paper by Orlando et al.
  • The commentary synthesizes existing knowledge on the noradrenergic system and saccadic function in PD.

Main Results:

  • The commentary emphasizes that noradrenergic pathways are implicated in the control of saccades.
  • It suggests that dysfunction in the noradrenergic system contributes to saccadic impairments observed in Parkinson's disease.
  • The findings by Orlando et al. provide insights into the specific mechanisms underlying these deficits.

Conclusions:

  • Noradrenergic modulation is a key factor in understanding saccade control in Parkinson's disease.
  • Targeting the noradrenergic system may offer novel therapeutic strategies for treating eye movement disorders in PD.
  • Further research is warranted to fully elucidate the role of noradrenergic neurotransmission in PD-related oculomotor dysfunction.