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Is it worth using the Comprehensive Complication Index over the Clavien-Dindo classification in elderly patients who
Alexandre Danilovic1, Gustavo Perrone2, Lucas Dias3
1Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Av. Dr. Eneas de Carvalho Aguiar, 255, 7 and. Sala 7175, São Paulo, SP, 05403-000, Brazil. alexandre.danilovic@hc.fm.usp.br.
Insights
The Comprehensive Complication Index (CCI) and Clavien-Dindo classification (CDC) similarly predict complications after percutaneous nephrolithotomy (PCNL) in elderly patients. However, CDC underestimates hospitalization costs compared to CCI.
Area of Science:
- Urology
- Surgical Outcomes
- Geriatric Medicine
Background:
- Percutaneous nephrolithotomy (PCNL) is a common procedure for kidney stones.
- Assessing postoperative complications in elderly patients undergoing PCNL is crucial.
- The Comprehensive Complication Index (CCI) and Clavien-Dindo classification (CDC) are used to grade surgical complications.
Purpose of the Study:
- To compare the efficacy of CCI and CDC in evaluating complications after PCNL in elderly patients.
- To identify predictors of postoperative complications in this specific demographic.
- To analyze the correlation of these indices with length of stay and emergency room admissions.
Main Methods:
- Retrospective cohort study of patients aged 60 years and older who underwent PCNL (2009-2020).
- Postoperative complications were assessed within 30 days.
- Both CDC and CCI were calculated; length of stay and emergency room admissions served as complication surrogates.
Main Results:
- 244 elderly patients were included (median age 65).
- 15.6% experienced postoperative complications, with 2.5% having multiple.
- Both CDC and CCI correlated significantly with length of stay and ER admissions.
- CDC underestimated hospitalization costs compared to CCI (p=0.049).
- Higher ASA physical status, Charlson Comorbidity Index, Guy's classification, and UTI history predicted complications.
Conclusions:
- CDC and CCI demonstrate comparable correlation with length of stay and ER admissions post-PCNL in the elderly.
- CCI provides a more comprehensive assessment of hospitalization costs than CDC.
- Elevated ASA physical status, Charlson Comorbidity Index, Guy's classification, and prior UTI are significant predictors of complications in this population.
Purpose:
To compare the Comprehensive Complication Index (CCI) to the Clavien-Dindo classification (CDC) in an elderly population who underwent percutaneous nephrolithotomy (PCNL) and to identify predictors of postoperative complications in this population.
Methods:
We conducted a retrospective cohort study involving patients 60 years and older who underwent PCNL at our Institution between 2009 and 2020. Postoperative complications were considered up to 30 days after surgery. Both CDC and CCI were calculated to assess patient outcomes. Length of stay (LOS) and admission to the emergency room (ER) were used as surrogates of postoperative complications.
Results:
We included 244 patients with a median age of 65 [63-69] years. 15.6% presented postoperative complications, and 2.5% multiple complications. LOS had a correlation coefficient of 0.29 (p < 0.001) and ER admissions had a coefficient of 0.27 (p < 0.001) with both CDC and CCI. Cost of hospitalization based on CDC underestimated CCI-based cost of hospitalization in 0.8% (p = 0.049). Higher American Society of Anesthesiology (ASA) physical status (p = 0.02), Charlson Comorbidity Index (p = 0.008), Guy's classification (p = 0.005), and history of urinary tract infection (UTI, p = 0.047) exhibited significant correlations with postoperative complications.
Conclusion:
Both CDC and CCI equally correlate with LOS and ER admissions following PCNL in elderly patients. However, CDC underestimates cost of hospitalization in comparison to CCI. We found higher ASA physical status, Charlson Comorbidity Index, Guy's classification, and history of UTI as predictors of postoperative complications after this procedure in this population.
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