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Updated: Jun 9, 2025
A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Scalp Metastasis From Renal Cell Carcinoma: A Rare Case With Rapid Progression
Mohammed S Alzahrani1, Abdulsamad O Alharbi1, Abdulaziz Alghamdi1
1Urology, King Fahd Armed Forces Hospital, Jeddah, SAU.
Abstract:
Renal cell carcinoma (RCC) is a common renal malignancy that frequently metastasizes, though cutaneous metastasis, particularly to the scalp, is rare and generally indicates a poor prognosis. We report a case of scalp metastasis from RCC in a 69-year-old man who presented with unexplained weight loss and painless hematuria. Imaging revealed a 12-cm renal mass with adrenal, pulmonary, and scalp metastases. The patient's condition rapidly deteriorated, and he died one month after the presentation. Hematogenous spread through Batson's plexus might be the primary mechanism of RCC dissemination to the scalp. While targeted therapies have improved the management of metastatic RCC, the prognosis for patients with skin metastases remains poor.
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