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Questionnaire survey on severe hypoglycemia in pediatric patients with diabetes-English version

Tatsuhiko Urakami1,2, Tomoyuki Hotsubo3, Yohei Ogawa4

  • 1Division of Pediatrics and Child Health, Nihon University School of Medicine, 30-1 Oyaguchi Kamicho, Itabashi-Ku, Tokyo 173-8610 Japan.

Diabetology International
|October 29, 2024
PubMed

Insights

Severe hypoglycemia (SH) in children with diabetes is rare but concerning, often occurring at night at home. Current treatments for SH appear insufficient, requiring further investigation and improved management strategies.

Area of Science:

  • Pediatric Endocrinology
  • Diabetes Management
  • Clinical Research

Background:

  • Severe hypoglycemia (SH) poses a significant risk in pediatric diabetes care.
  • Understanding the incidence and characteristics of SH in children is crucial for effective management.
  • This study investigates SH events in Japanese pediatric diabetes patients.

Observation:

  • A survey of 33 hospitals identified 17 treating eligible patients under 15 years (506 type 1, 302 type 2 diabetes).
  • 25 SH events were reported between January 2017 and December 2021.
  • SH predominantly occurred in adolescents (10-15 years) at home during nighttime (0:00-8:00 a.m.).

Findings:

  • The estimated incidence of SH was 0.01 per patient per year.
  • Adolescents experienced SH more frequently than younger children.
  • Most SH events occurred at home overnight, with limited occurrences during school hours.

Implications:

  • Current treatment protocols for severe hypoglycemia in pediatric patients may be insufficient.
  • There is a need for enhanced strategies to prevent and manage SH, particularly during nighttime and at home.
  • Further research is warranted to optimize SH management in children with diabetes.

Keywords:
Childhood diabetesPatient educationQuestionnaire surveySevere hypoglycemiaType 1 diabetes

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