Three-Dimensional Speckle Tracking Echocardiography Assessment of Right Ventricular Function in Chronic Coronary

WenShu Hu1, Chang Zhou1, Heng Sun1

  • 1Department of Ultrasound, The First College of Clinical Medical Science, China Three Gorges University, Yichang, Hubei, China.

PubMed

Insights

Percutaneous coronary intervention (PCI) improves right ventricular (RV) function in chronic coronary syndrome patients within six months. However, RV free wall longitudinal strain (RVFWLS) remains lower than controls at 12 months post-PCI.

Area of Science:

  • Cardiology
  • Echocardiography
  • Cardiac Function Assessment

Background:

  • Chronic coronary syndromes can impact cardiac function.
  • Percutaneous coronary intervention (PCI) is a common treatment for coronary artery disease.
  • Assessing right ventricular (RV) function post-PCI is crucial for patient outcomes.

Purpose of the Study:

  • To evaluate changes in RV systolic function after PCI in patients with chronic coronary syndromes.
  • To compare RV function metrics between patients and healthy controls.
  • To assess the utility of three-dimensional speckle tracking echocardiography (3D-STE) in monitoring RV function post-PCI.

Main Methods:

  • A prospective study included 136 patients undergoing PCI for chronic coronary syndromes and 110 healthy controls.
  • Echocardiography, including conventional and 3D-STE, was performed at 1 week, 6 months, and 12 months post-PCI.
  • Key parameters measured included TAPSE, S', RVFAC, RVFWLS, RVGLS, RVSV, and RVEF.

Main Results:

  • Significant improvements in RV function parameters (TAPSE, S', RVFAC, RVGLS, RVSV, RVEF) were observed from 1 week to 6 months post-PCI.
  • While some parameters showed no significant change between 6 and 12 months, TAPSE, S', and RVFWLS continued to increase significantly.
  • At 12 months, RVFWLS remained significantly lower in patients compared to healthy controls, despite other RV function metrics showing no significant difference.

Conclusions:

  • Right ventricular systolic function significantly improves after PCI in chronic coronary syndrome patients.
  • RVFWLS remains a potential indicator of persistent RV dysfunction post-PCI.
  • 3D-STE is a valuable noninvasive tool for quantifying RV systolic function in this patient population.
Abstract

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