Related Experiment Video

Updated: Jun 9, 2025

Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty
10:03

Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty

Published on: January 28, 2020

5.2K

The role of systemic immune-inflammatory index in predicting contrast-induced nephropathy in non-ST-segment elevation

Ozan Tezen1, Mert İlker Hayıroğlu2, Levent Pay3

  • 1Department of Cardiology, Bayrampasa State Hospital, Istanbul, Turkey.

Biomarkers in Medicine
|October 29, 2024
PubMed

Insights

The systemic immune-inflammation index (SII) can predict contrast-induced nephropathy (CIN) in non-ST-segment elevation myocardial infarction (NSTEMI) patients. A high SII value indicates a significant risk for developing CIN after procedures.

Area of Science:

  • Cardiology
  • Nephrology
  • Immunology

Background:

  • Contrast-induced nephropathy (CIN) is a complication following contrast media exposure.
  • Non-ST-segment elevation myocardial infarction (NSTEMI) patients are at risk for CIN.
  • The systemic immune-inflammation index (SII) reflects systemic inflammation.

Purpose of the Study:

  • To investigate the association between SII and CIN development in NSTEMI patients.
  • To determine if SII can serve as a predictive marker for CIN.

Main Methods:

  • A cohort of 1124 NSTEMI patients was analyzed.
  • Patients were categorized into two groups based on CIN development.
  • The relationship between SII and CIN incidence was statistically examined.

Main Results:

  • Significant differences in age, chronic renal failure, LAD stenosis, SII, and CRP were noted between groups.
  • An SII value of 709 or higher demonstrated predictive capability for CIN.
  • The predictive power for CIN was 74% sensitivity and 74% specificity.

Conclusions:

  • The systemic immune-inflammation index (SII) shows potential as a predictor of CIN in NSTEMI patients.
  • Elevated SII levels may indicate an increased risk for contrast-induced nephropathy.

Keywords:
contrast induced nephropathynon-ST segment elevated myocardial infarctionsystemic immune-inflammation index

More Related Videos

Herbal Munziq Ameliorates Myocardial Ischemia-Reperfusion Injury by Inhibiting Inflammation09:53

Herbal Munziq Ameliorates Myocardial Ischemia-Reperfusion Injury by Inhibiting Inflammation

Published on: January 10, 2025

332
Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response12:50

Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response

Published on: September 15, 2017

6.5K

Related Concept Videos

Myocarditis I: Introduction01:21

Myocarditis I: Introduction

Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
2
Myocarditis II: Clinical features and Diagnostic Tests01:27

Myocarditis II: Clinical features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
2
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
61
Myocarditis IV: Nursing Management01:22

Myocarditis IV: Nursing Management

Myocarditis is an inflammatory condition of the myocardium requiring meticulous nursing management for optimal patient outcomes. Effective management begins with a thorough assessment of the patient's medical history, paying close attention to past infections, autoimmune disorders, travel history, and exposure to toxins or drugs. Recent viral infections and systemic diseases are particularly relevant due to their potential role in triggering myocarditis.Physical Examination and MonitoringThe...
2
Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
2
Acute Coronary Syndrome III: Diagnostic studies01:30

Acute Coronary Syndrome III: Diagnostic studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
3