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Updated: Jun 9, 2025

Increasing Pulmonary Artery Pulsatile Flow Improves Hypoxic Pulmonary Hypertension in Piglets
Published on: May 11, 2015
Pulmonary Artery Denervation: An Emerging Treatment for Pulmonary Hypertension
Matthew W McMaster1, Avisha Shah2, Yosef Hassid1
1From the Department of Medicine, Westchester Medical Center and New York Medical College, Valhalla, NY.
Abstract:
Pulmonary hypertension (PH) is a debilitating disease with a poor overall prognosis. Pulmonary artery denervation (PADN) has emerged as a promising new treatment which has been shown to improve hemodynamics, functionality, and REVEAL scores for patients with PH. This article reviews notable updates in the management of PH since the 6th World Symposium on PH, the pathophysiology of PH, how PADN may work given the pathophysiology of PH, and focuses on evidence from the eleven studies supporting the use of PADN from trials that include human participants.
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