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Updated: Dec 9, 2025
Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples
Published on: January 21, 2018
Difference between real world practice and clinical research: A comparison of oropharyngeal and nasopharyngeal
Tongyan Zhang1, Yajun Du2, Yanyan Ren1
1Tianjin University of Traditional Chinese Medicine, Tianjin, China; Infectious Diseases Department, Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Abstract:
Oropharyngeal (OP) sampling is one of the most commonly used methods for respiratory sampling, but its positivity rate in real practice compared with that of nasopharyngeal (NP) sampling is not fully known. The differences between OP and NP in practice and between practice and the literature were compared. In total, 2323 positive results from 6708 patients were recorded in the laboratory test system, and 15,021 positive results from 31,333 patients were recorded in the national report. The positivity rate changed from 2.3 % to 38.11 % after the sampling method was changed from OP to NP in the same setting. The difference between OP and NP (calculated as (NP-OP)/NP) varies from -7.73-28.57 % in the literature and from 61.35-94.59 % in practice. Real-world practice is complicated and thus different from strictly quality-controlled studies.
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