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Related Experiment Videos

Neonatal paralytic poliomyelitis. A case report.

G H Bergeisen, R J Bauman, R L Gilmore

    Archives of Neurology
    |February 1, 1986
    PubMed
    Summary
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    Neonatal poliomyelitis, a rare disease, has re-emerged in the US. Poliovirus vaccine type caused apnea and permanent leg weakness in an infant, highlighting the need for accurate diagnosis.

    Area of Science:

    • Pediatrics
    • Infectious Diseases
    • Virology

    Background:

    • Neonatal poliomyelitis was historically rare, with no reported US cases since the widespread adoption of the live oral poliovirus vaccine (Sabin's vaccine).
    • The continued circulation of poliovirus, even vaccine-derived strains, poses a potential risk for vulnerable infant populations.

    Observation:

    • A case of neonatal poliomyelitis is reported in the United States.
    • The infant presented with apnea at 18 days of age and later developed permanent monoparesis.

    Findings:

    • Serologic and cultural evidence confirmed the causative agent as poliovirus vaccine type.
    • Transmission likely occurred from another infant who received the live oral poliovirus vaccine.

    Implications:

    Related Experiment Videos

    • This case underscores that poliovirus infections can still occur in the United States.
    • Accurate diagnosis requires awareness and appropriate serologic, cultural, and typing tests for suspected cases.
    • Prompt recognition and diagnosis are crucial for managing and preventing further spread of poliovirus in neonates.