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Updated: Jun 9, 2025

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations
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New insight into the development of synpolydactyly caused by expansion of HOXD13 polyalanine based on weighted gene

Xiumin Chen1, Xiaofang Shen2, Tao Yang1

  • 1McKusick-Zhang Center for Genetic Medicine, State Key Laboratory for Complex Severe and Rare Diseases, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, 100005, China.

BMC Medical Genomics
|October 30, 2024
PubMed
Abstract

Keywords:
HOXD13SynpolydactylyImmune responsePolyalanine expansionSingle-cell RNA sequencing

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