Acute Febrile Illness in India: An Epidemiological Retrospective Study.

Area of Science:

• Clinical Medicine
• Biochemistry
• Hematology

Background:

• Acute febrile illness (AFI) is common in India, often with complex causes.
• Understanding AFI's clinical, biochemical, and hematological profiles is crucial for effective management.

Purpose of the Study:

• To analyze biochemical, hematological, and epidemiological parameters in North Indian AFI patients.
• To establish a baseline for etiological factors and correlations in AFI.

Main Methods:

• Analysis of 211 AFI patients (aged 2-85) from 2017-2021.
• Collection of clinical, respiratory, blood, and urine samples for biochemical and hematological analysis.
• Statistical analysis including regression and Karl-Pearson correlation.

Main Results:

• Key biochemical markers (CRP, ALP, SGPT, SGOT, GGT, total protein) and hematological parameters (TLC, RBCs, PCV, ESR, MCV, MCH) were measured.
• Observed values for SGPT, SGOT, GGT, and total protein serum were documented.
• Regression analysis explored relationships between admission temperature, hospital stay duration, and measured variables.

Conclusions:

• Systematic assessment of etiological factors in AFI patients using biochemical and hematological data.
• Highlights the need for further research into infection pathways and preventive strategies.
• Provides foundational data for developing natural product-based interventions for AFI.