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Cardiovascular Mortality Risk Among Patients with Liver Cancer: A SEER Database Study
Juan Li1, Junyong Zhang2, Song He1
1The Second Affiliated Hospital of Chongqing Medical University, Department of Gastroenterology, Chongqing, China.
Abstract:
Crucial for understanding liver cancer patients overall health outcomes. This research aimed to assess the CVM risk of them.
Methods And Materials:
Data sourced from the Surveillance, Epidemiology, and End Results (SEER) database encompassing liver cancer diagnoses from 2000 to 2017 were utilized. The standardized mortality rate (SMR) was computed using general population reference data, and multivariate competing risk models were employed for analysis.
Results:
Analysis of 70,733 liver cancer patient records revealed 1,954 instances of CVM. The overall CVM SMR for liver cancer patients was 12.01 (95% CI: 11.48-12.55). Various demographic and clinical factors, including sex, race, age, year of diagnosis, pathological type, general stage, treatment modalities, and matrimonial status, emerged as liver cancer patients` independent predictors of CVM.
Conclusion:
Liver cancer patients have a notably heightened susceptibility to cardiovascular mortality (CVM) in contrast to the general populace. It is imperative to promptly recognize high-risk subcategories and execute tailored cardiovascular interventions as crucial measures to bolster survival rates within this cohort of patients.
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