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A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
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Contribution of Rare and Potentially Functionally Relevant Sequence Variants in Schizophrenia Risk-Locus Xq28,distal

I Claus1, S Sivalingam2,3,4,5, A C Koller1

  • 1Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany.

American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics
|October 30, 2024
PubMed
Summary

Researchers investigated rare genetic variants in the Xq28 distal locus for schizophrenia (SCZ) risk. The study found no significant association between these variants and SCZ in European cohorts, suggesting other factors may be involved.

Keywords:
X‐chromosomeburden analysiscopy number variationrare variantsschizophrenia

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