Association between central corneal thickness and systemic lupus erythematosus: a cross-sectional study protocol
Juan David Saldaña-Garrido1,2, Mario Cantó-Cerdán3, Vicente Francisco Gil-Guillén2,4
1Department of Ophthalmology, General University Hospital of Elda, Elda, Spain.
Systemic lupus erythematosus (SLE) may decrease central corneal thickness (CCT), increasing glaucoma risk. This study compares CCT in SLE patients and controls to clarify this ocular complication.
Area of Science:
- Ophthalmology
- Rheumatology
- Autoimmune Diseases
Background:
- Systemic lupus erythematosus (SLE) is an autoimmune disease affecting multiple systems.
- Ocular involvement occurs in up to 30% of SLE cases, with the cornea being particularly susceptible to thinning.
- Reduced central corneal thickness (CCT) is a risk factor for glaucoma.
Purpose of the Study:
- To determine and compare mean CCT values between SLE patients and healthy controls.
- To investigate the potential relationship between SLE and decreased CCT.
- To enhance methodological rigor in studying CCT in SLE.
Main Methods:
- Cross-sectional observational study design.
- Enrollment of SLE patients and age/sex-matched healthy controls.
- Central corneal thickness (CCT) measurement using optical coherence tomography (OCT).
Main Results:
- This section is to be filled once the study is completed and results are available.
Conclusions:
- This section is to be filled once the study is completed and conclusions are drawn.
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