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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...

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CHA2DS2-VASc Score in Predicting Visual Acuity Outcomes Following Retinal Vein Occlusion.

Achia Nemet1,2, Raimo Tuuminen3,4,5, Tzadok Yona6

  • 1Department of Ophthalmology, Assuta Ashdod University Medical Center, Ashdod, Israel.

Journal of Ophthalmology
|October 30, 2024
PubMed
Summary

The CHA₂DS₂-VASc score, used for atrial fibrillation stroke risk, predicts visual acuity outcomes after retinal vein occlusion (RVO). Higher scores (≥6) indicate a poorer visual prognosis in RVO patients.

Keywords:
CHA2DS2-VASc scoreretinal vein occlusionvisual acuity

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Area of Science:

  • Ophthalmology
  • Cardiology
  • Vascular Medicine

Background:

  • Retinal vein occlusion (RVO) is a significant cause of vision loss.
  • The CHA₂DS₂-VASc score is established for assessing stroke risk in atrial fibrillation.
  • The prognostic value of the CHA₂DS₂-VASc score in RVO visual outcomes is not well-defined.

Purpose of the Study:

  • To investigate the correlation between the CHA₂DS₂-VASc score and visual acuity prognosis in patients with RVO.
  • To determine if a higher CHA₂DS₂-VASc score predicts poorer visual outcomes following RVO.

Main Methods:

  • Retrospective analysis of 83 patients diagnosed with branch or central RVO.
  • Patients stratified into three groups based on CHA₂DS₂-VASc scores: 0-2, 3-5, and 6-9.
  • Best-corrected visual acuity (BCVA) changes evaluated at 1-year follow-up post-RVO.

Main Results:

  • Patients with CHA₂DS₂-VASc scores of 6-9 exhibited significantly worse BCVA prognosis at 1 year compared to lower score groups.
  • The mean visual acuity change for the high-score group (6-9) was +0.60 LogMAR units.
  • Lower CHA₂DS₂-VASc scores (0-2 and 3-5) were associated with stable or improved visual acuity.

Conclusions:

  • A CHA₂DS₂-VASc score of 6 or higher is associated with a poorer visual acuity prognosis after RVO.
  • The CHA₂DS₂-VASc score may serve as a useful tool for predicting visual outcomes in RVO patients.
  • Further research could explore the underlying mechanisms linking systemic vascular risk factors to RVO prognosis.