Sleep Efficiency and Neurocognitive Decline in Atopic Dermatitis: A Systematic Review

Area of Science:

• Dermatology
• Neuroscience
• Sleep Medicine

Background:

• Atopic dermatitis (AD) is frequently associated with diminished sleep efficiency.
• Sleep disturbances in AD may negatively impact neurocognitive functions.

Purpose of the Study:

• To review the association between sleep quality in atopic dermatitis patients and neurocognitive decline.
• To synthesize current evidence on the relationship between AD, sleep, and cognition.

Main Methods:

• Systematic literature search of PubMed, Scopus, and Web of Science up to January 8, 2024.
• Inclusion of cross-sectional and longitudinal studies following PRISMA guidelines.
• Analysis of 13 studies involving 272,868 participants.

Main Results:

• Consistent sleep disruption observed in individuals with atopic dermatitis.
• Association found between poor sleep quality and short-term neurocognitive deficits (e.g., impaired focus, lower IQ).
• Limited evidence suggests potential long-term cognitive decline in chronic AD.

Conclusions:

• Lower sleep quality in atopic dermatitis is significantly linked to neurocognitive deficits.
• Immediate cognitive effects are evident, but long-term consequences warrant further investigation.
• Integrating sleep management strategies into atopic dermatitis treatment plans is crucial.