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Efficacy and Safety Assessment of LVIS Jr Device in Treating Wide-Neck Aneurysms: A Comprehensive Systematic Review
Marcelo Porto Sousa1, Guilherme Nunes Marques, Livia Abreu
1Federal University of Rio de Janeiro, Faculty of Medicine, Rio de Janeiro - Rio de Janeiro, Brazil.
Aim:
To evaluate the usage and the effectiveness of LVIS Jr device technology in managing wide-neck intracranial aneurysms.
Material And Methods:
PubMed, Embase, and Web of Science databases, comprising studies with outcomes related to LVIS Jr use in wide-neck intracranial aneurysms were searched systematically. Data was extracted from the selected articles and subjected to statistical analysis.
Results:
Among 886 initially identified articles, 20 studies met our inclusion criteria, comprising a total of 557 patients. Our analysis revealed a 96% final occlusion rate under common effects and 93% under random effects, with substantial heterogeneity (I² = 69%). Good clinical outcomes were observed in 99% of cases with low heterogeneity (I² = 27%). Mortality rates were extremely low, with only one reported death out of 499 patients across 18 studies, resulting in a 0% mortality rate for common and random effects and no heterogeneity (I² = 0). Complications occurred in 44 of 482 patients, yielding a 6% rate in the common effect model and 6% in the random effects model, with nonsignificant heterogeneity (I² = 25%).
Conclusion:
LVIS Jr observed a favorable rate of final occlusion and good clinical outcomes, and the low mortality and complication rates highlight its safety in the treatment of wide-neck aneurysms.
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