Predictive Value of PHRI for Recurrence within One Year after UC Treatment: A Retrospective Study

Area of Science:

• Gastroenterology
• Endoscopic assessment
• Inflammatory Bowel Disease (IBD) research

Background:

• Accurate prediction of ulcerative colitis (UC) recurrence is vital for patient prognosis.
• Mucosal healing assessment, using scores like PICaSSO and PHRI, is key in UC management.
• The predictive value of the PHRI for short-term UC recurrence requires further investigation.

Purpose of the Study:

• To explore the predictive value of the PHRI for short-term recurrence in UC patients.
• To identify risk factors associated with UC recurrence in patients in clinical remission.
• To provide a reference for improving the prognosis of UC patients.

Main Methods:

• Retrospective analysis of clinical data from 102 UC patients in clinical remission.
• Patients were categorized into recurrence and non-recurrence groups based on one-year follow-up.
• Multivariate logistic regression and ROC curve analysis were used to assess predictive value.

Main Results:

• 35.29% of UC patients experienced recurrence within one year.
• Lesion extent, disease severity, colonoscopy score, and PHRI score were independent risk factors for recurrence.
• The PHRI score demonstrated good predictive value (AUC = 0.838) with high sensitivity (89.58%) and specificity (65.58%) at a cut-off of 1.

Conclusions:

• Lesion extent, disease severity, endoscopic score, and PHRI score are associated with one-year recurrence in UC patients.
• The PHRI score is a valuable tool for predicting short-term recurrence in UC patients in clinical remission.