Sugar Highs: Recent Notable Breakthroughs in Glycobiology
Jimin Hu1, Duc T Huynh1, Michael Boyce1
1Department of Biochemistry, Duke University School of Medicine, Durham, North Carolina 27710, United States.
Abstract:
Glycosylation is biochemically complex and functionally critical to a wide range of processes and disease states, making it a vibrant area of contemporary research. Here, we highlight a selection of notable recent advances in the glycobiology of SARS-CoV-2 infection and immunity, cancer biology and immunotherapy, and newly discovered glycosylated RNAs. Together, these studies illustrate the significance of glycosylation in normal biology and the great promise of manipulating glycosylation for therapeutic benefit in disease.
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