Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Antidepressant Drugs: MAOIs and Other Agents01:23

Antidepressant Drugs: MAOIs and Other Agents

196
Atypical antidepressants, including bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), and vilazodone (Viibryd), offer unique mechanisms of action. Bupropion weakly inhibits dopamine and norepinephrine reuptake, aiding depression treatment and smoking cessation, with a low risk of sexual dysfunction. Mirtazapine enhances serotonin and norepinephrine neurotransmission, leading to sedation, increased appetite, and weight gain. As a result, it helps treat...
196
Cognitive Therapy01:25

Cognitive Therapy

146
Cognitive therapy, pioneered by Aaron T. Beck in the 1960s, is a structured approach to addressing psychological distress by focusing on the influence of thoughts on emotions and behaviors. All cognitive therapies involve the basic assumption that human beings have control over their feelings, and that how individuals feel about something depends on how they think about it. Unlike psychoanalytic methods that delve into unconscious processes or humanistic approaches emphasizing...
146
Electroconvulsive Therapy01:30

Electroconvulsive Therapy

25
Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
25
Modeling in Therapy01:26

Modeling in Therapy

49
Modeling, a key technique in therapy, uses observational learning to help clients acquire and practice new skills by watching therapists demonstrate desired behaviors. This approach, rooted in Albert Bandura's concept of vicarious learning, plays a significant role in therapeutic interventions for various psychological conditions, including social anxiety, ADHD, and depression.
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...
49
Interpersonal Psychotherapy01:25

Interpersonal Psychotherapy

22
Interpersonal psychotherapy (IPT) is a structured, time-limited therapeutic approach initially developed to treat depression. It integrates key concepts from psychodynamic, humanistic, and cognitive-behavioral therapies, making it a uniquely eclectic framework. The therapy is rooted in the interpersonal theories of Adolph Meyer and Harry Stack Sullivan, as well as John Bowlby's attachment theory, and focuses on the interplay between interpersonal relationships and emotional well-being.
22
Depression: Overview01:18

Depression: Overview

222
Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
222

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mechanisms of mindfulness-based cognitive therapy in difficult-to-treat depression: moderation and mediation analyses from the RESPOND trial.

Psychological medicine·2026
Same author

Identifying distinct trajectories of change in anhedonia during psychological treatment for depression.

Psychological medicine·2026
Same author

Effects on hippocampal activity following novel 5-HT4 receptor agonism in unmedicated patients with depression: the RESTAND study.

Translational psychiatry·2026
Same author

The efficacy of an online self-administered single session intervention to promote growth mindset in adolescents: A randomised controlled trial.

JCPP advances·2026
Same author

Exploring fatigue in clinically depressed adolescents: a secondary analysis of the IMPACT study sample.

BMC psychology·2026
Same author

Efficacy and Moderators of Mindfulness-Based Cognitive Therapy in Difficult-to-Treat Depression: A Systematic Review and Individual Participant Data Meta-Analysis.

Psychotherapy and psychosomatics·2026

Related Experiment Video

Updated: Jun 9, 2025

Polar Histogram Visualization of Acute Stress Disorder Scale Scores for Comprehensive Clinical Assessment
08:25

Polar Histogram Visualization of Acute Stress Disorder Scale Scores for Comprehensive Clinical Assessment

Published on: December 6, 2024

313

Augmented Depression Therapy for young adults: A mixed methods randomised multiple baseline case series evaluation.

James Carson1, Kalliopi Demetriou2, Gemma Barlow1

  • 1Mood Disorders Centre, University of Exeter, UK.

Behaviour Research and Therapy
|October 30, 2024
PubMed
Summary

Augmented Depression Therapy (ADepT) is a feasible and acceptable psychotherapy for young adults experiencing depression. While safe, modifications may enhance its effectiveness in this demographic.

Keywords:
AnhedoniaAugmented depression therapyDepressionPositive affectWellbeingYoung adults

More Related Videos

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression
08:42

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression

Published on: May 19, 2015

10.4K
Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method
07:12

Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method

Published on: August 2, 2021

3.5K

Related Experiment Videos

Last Updated: Jun 9, 2025

Polar Histogram Visualization of Acute Stress Disorder Scale Scores for Comprehensive Clinical Assessment
08:25

Polar Histogram Visualization of Acute Stress Disorder Scale Scores for Comprehensive Clinical Assessment

Published on: December 6, 2024

313
Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression
08:42

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression

Published on: May 19, 2015

10.4K
Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method
07:12

Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method

Published on: August 2, 2021

3.5K

Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Mental Health Research

Background:

  • Augmented Depression Therapy (ADepT) is an established psychotherapy for adult depression.
  • Young adults represent a critical demographic for mental health interventions.
  • The COVID-19 pandemic presented unique challenges for mental healthcare delivery.

Purpose of the Study:

  • To evaluate the feasibility, acceptability, and effectiveness of ADepT in young adults (20-24 years old).
  • To assess ADepT's safety and patient-reported outcomes during the COVID-19 pandemic.

Main Methods:

  • A randomised multiple baseline case series design was employed.
  • Eleven depressed young adults from a UK university wellbeing service participated.
  • Outcomes were measured against pre-specified continuation targets, including feasibility, acceptability, and clinical improvement.

Main Results:

  • All participants received adequate treatment dose; 89% found ADepT acceptable and recommendable.
  • Only 9% experienced reliable deterioration; no serious adverse events were reported.
  • Post-treatment, 33% showed reliable depression improvement and 67% wellbeing improvement, with medium to large effect sizes.

Conclusions:

  • ADepT is feasible, acceptable, and safe for young adults with depression.
  • While demonstrating promise, ADepT may require modifications to optimize effectiveness in this population.
  • Further research is recommended, particularly outside of pandemic conditions.