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Letter to the Editor Regarding the Article "Circulating MicroRNAs May be Predictive of Degenerative Cervical

Xian-Min Bu1, Bin Wu2

  • 1Department of Pathology, Jining No. 1 People's Hospital, Jining City, Shandong Province, China.

Spine
|October 30, 2024
PubMed
Abstract

No abstract available in PubMed .

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MicroRNAs01:22

MicroRNAs

MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of DNA present between genes. Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA ends...