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Updated: Jun 9, 2025

Rare Event Detection Using Error-corrected DNA and RNA Sequencing
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Neglecting the impact of normalization in semi-synthetic RNA-seq data simulations generates artificial false

Boris P Hejblum1,2, Kalidou Ba3,4, Rodolphe Thiébaut3,4,5

  • 1Univ. Bordeaux, INSERM Bordeaux Population Health Research Center, U1219, INRIA SISTM, Bordeaux, F-33000, France. boris.hejblum@u-bordeaux.fr.

Genome Biology
|October 31, 2024
PubMed

Keywords:
Differential expression analysisHuman population samplesRNA-seq data simulationRelated research article

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