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Oral Plexiform Neurofibroma Involving the Buccal Mucosa: A Case Report
N Fazulunnisa Begum1, Karthikeyan Ramalingam1, Pratibha Ramani1
1Oral Pathology and Microbiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Cureus
|October 31, 2024
Summary
Oral plexiform neurofibromas, benign peripheral nerve tumors, can recur even after complete surgical removal. Understanding recurrence mechanisms is crucial for better patient management and outcomes.
Area of Science:
- Oral pathology
- Surgical oncology
- Neurosurgery
Background:
- Oral plexiform neurofibroma is a benign peripheral nerve tumor characterized by a 'plexus' or 'bag of worms' appearance.
- These tumors carry a significant risk of recurrence and malignant transformation.
- Early detection and management are vital for patient prognosis.
Observation:
- A case report details a young male diagnosed with oral plexiform neurofibroma on the buccal mucosa.
- The patient underwent a full-body examination to screen for neurofibromatosis.
- Despite surgical excision, the potential for high recurrence rates remains a concern.
Findings:
- Surgical excision is the primary treatment for oral plexiform neurofibromas.
- Recurrence can occur even after seemingly complete surgical removal.
- Involvement of critical anatomical structures may impede complete excision, contributing to recurrence.
Implications:
- Further investigation into the pathogenesis of oral plexiform neurofibroma recurrence is necessary.
- Improved understanding can lead to enhanced surgical strategies and more effective treatment protocols.
- This knowledge is essential for optimizing patient outcomes and minimizing long-term morbidity.
