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Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
Published on: December 3, 2017
Management of the infected total elbow arthroplasty
1Division of Shoulder and Elbow Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Abstract:
Periprosthetic joint infection represents a devastating complication after total elbow arthroplasty. Several measures can be implemented before, during, and after surgery to decrease infection rates, which exceed 5%. Debridement with antibiotics and implant retention has been reported to be successful in less than one-third of acute infections, but still plays a role. For elbows with well-fixed implants, staged retention seems to be equally successful as the more commonly performed two-stage reimplantation, both with a success rate of 70% to 80%. Permanent resection or even amputation are occasionally considered. Not uncommonly, a second-stage reimplantation requires complex reconstruction of the skeleton with allografts, and the extensor mechanism may also be deficient. Further developments are needed to improve our management of infection after elbow arthroplasty.
Insights
Periprosthetic joint infection is a severe complication following total elbow replacement. Strategies exist to reduce infection rates, with some treatments showing moderate success but requiring further development.
Area of Science:
- Orthopedic Surgery
- Infectious Diseases
- Biomaterials
Background:
- Periprosthetic joint infection (PJI) is a significant complication after total elbow arthroplasty, with infection rates exceeding 5%.
- Managing PJI after elbow arthroplasty presents unique challenges, often leading to complex surgical interventions and potentially poor outcomes.
- Existing treatment options have variable success rates, highlighting the need for improved management strategies.
Purpose of the Study:
- To review current strategies for preventing and managing periprosthetic joint infection after total elbow arthroplasty.
- To evaluate the efficacy of different surgical approaches, including debridement with antibiotic retention and staged reimplantation.
- To identify areas for future research and development in the management of elbow PJI.
Main Methods:
- Review of current literature on periprosthetic joint infection in total elbow arthroplasty.
- Analysis of treatment outcomes for debridement with antibiotic retention, staged reimplantation, and other surgical options.
- Discussion of challenges related to complex reconstructions and extensor mechanism deficiencies.
Main Results:
- Debridement with antibiotic retention shows limited success in acute infections (less than one-third).
- Staged retention and two-stage reimplantation demonstrate comparable success rates (70-80%) for elbows with well-fixed implants.
- Complex reconstructions with allografts and extensor mechanism deficits are common challenges in second-stage reimplantation.
Conclusions:
- Effective management of periprosthetic joint infection after total elbow arthroplasty requires a multi-faceted approach.
- While some surgical options offer moderate success, significant challenges remain, particularly in complex cases.
- Further advancements in treatment protocols and surgical techniques are crucial to improve outcomes for patients with elbow PJI.
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