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Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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A Novel Vertebral Stabilization Method for Producing Contusive Spinal Cord Injury

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Published on: January 5, 2015

Defining multilevel developmental cervical spinal stenosis using MRI.

Prudence W H Cheung¹, Justin H M Leung¹, Vivien W Y Lee¹

¹Department of Orthopaedics and Traumatology, The University of Hong Kong, Hong Kong SAR, China.

The Bone & Joint Journal

|October 31, 2024

Summary

This summary is machine-generated.

Developmental cervical spinal stenosis (DcSS) is defined by MRI criteria, with 13% of the general population exhibiting multilevel DcSS. Multilevel DcSS and male sex are key predictors for developing degenerative cervical myelopathy (DCM).

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Area of Science:

Spinal Imaging and Diagnostics
Neurology and Neurosurgery
Public Health and Epidemiology

Background:

Developmental cervical spinal stenosis (DcSS) is a known risk factor for degenerative cervical myelopathy (DCM).
A clear, MRI-based definition for DcSS and its prevalence remain undefined, hindering risk assessment.
Understanding DcSS characteristics is crucial for predicting DCM development.

Purpose of the Study:

To establish an MRI-based definition for DcSS, including its multilevel characteristics.
To determine the prevalence of DcSS in the general population.
To evaluate DcSS as a predictor for the development of DCM.

Main Methods:

Cross-sectional analysis of cervical spine MRI (C3-C7) from 95 DCM patients and 2,019 general population individuals.
Defined DcSS as multilevel (≥3 levels) spinal canal anteroposterior diameter below DCM patient median values.
Utilized receiver operating characteristic analysis for optimal cut-off diameters and logistic regression for DCM prediction.

Main Results:

Established optimal MRI cut-off diameters for DcSS: C3 < 12.9mm, C4 < 11.8mm, C5 < 11.9mm, C6 < 12.3mm, C7 < 13.3mm.
Multilevel DcSS was identified in 13.0% (262/2,019) of the general population cohort.
Multilevel DcSS (OR 6.12) and male sex (OR 4.06) significantly predicted DCM development.

Conclusions:

This study provides the first MRI-based definition for multilevel DcSS.
Level-specific cut-off diameters enable early identification of individuals at risk for DCM.
Individuals with multilevel DcSS and males warrant close monitoring or early intervention to prevent spinal cord injury.