Cost-effectiveness of strengthening blood pressure classification in South Korea: comparing the 2017 ACC/AHA and KSH

KyungYi Kim1, Min Ji Hong2, Bomgyeol Kim3

  • 1Department of Healthcare Management, Graduate School of Public Health, Yonsei University, 50-1, Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.

Clinical Hypertension
|November 1, 2024
PubMed

Insights

Adopting the 2017 ACC/AHA hypertension guidelines in South Korea is cost-effective, potentially reducing cardiovascular disease (CVD) events. This approach offers significant public health benefits and supports policy decisions on blood pressure targets.

Area of Science:

  • Health Economics
  • Public Health Policy
  • Cardiovascular Disease Prevention

Background:

  • Hypertension significantly increases cardiovascular disease (CVD) risk, with rising mortality rates.
  • South Korea currently follows the Korean Society of Hypertension (KSH) guideline (140/90 mmHg).
  • The 2017 ACC/AHA guidelines recommend a lower threshold (130/80 mmHg).

Purpose of the Study:

  • To evaluate the cost-effectiveness of adopting the 2017 ACC/AHA hypertension guidelines in South Korea.
  • To estimate the impact of earlier blood pressure treatment on CVD risk reduction.
  • To inform policy decisions regarding hypertension management guidelines.

Main Methods:

  • A 10-year Markov state-transition simulation model was employed.
  • Quality-adjusted life years (QALYs) were used to measure effectiveness.
  • Analyses compared cohorts of 10,000 individuals across age groups (20s-80s) from a healthcare system perspective.

Main Results:

  • The base-case incremental cost-effectiveness ratio (ICER) was KRW 1,328,395/QALY gained.
  • ICERs varied by age, with younger individuals showing negative ICERs (cost-saving) and older individuals showing higher positive ICERs.
  • All scenarios remained below the willingness-to-pay threshold, with a 98.0% probability of cost-effectiveness.

Conclusions:

  • Adopting the 2017 ACC/AHA guidelines is projected to be cost-effective across all South Korean age groups.
  • Implementing these guidelines may lead to earlier hypertension treatment and reduced CVD incidence.
  • Findings provide crucial economic data for policymakers considering guideline revisions.
Abstract

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