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Related Concept Videos

Herniated Intervertebral Disc l: Introduction01:29

Herniated Intervertebral Disc l: Introduction

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Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
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Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
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Degenerative Disc Disease ll: Pathophysiology01:23

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The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...
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Related Experiment Video

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Ovine Lumbar Intervertebral Disc Degeneration Model Utilizing a Lateral Retroperitoneal Drill Bit Injury
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Lumbar intervertebral disc replacement in Australia: An epidemiological study.

Zac Dragan1, Adam R George1, Ryan J Campbell2

  • 1Faculty of Medicine and Health, The University of Sydney, Sydney Medical School, Faculty of Medicine and Health, Camperdown, New South Wales, Australia.

Journal of Craniovertebral Junction & Spine
|November 1, 2024
PubMed
Summary

Lumbar intervertebral total disc replacement (L-TDR) uptake in Australia has declined since 2021. Future use of L-TDR depends on more comprehensive long-term outcome data.

Keywords:
Degenerative disc diseaseintervertebral disc replacementlower back painlumbar spine

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Area of Science:

  • Spinal surgery
  • Orthopedics
  • Health services research

Background:

  • Lumbar intervertebral total disc replacement (L-TDR) shows favorable short- and long-term outcomes.
  • Evidence on the practical adoption of L-TDR is limited.

Purpose of the Study:

  • To analyze Australian population trends in L-TDR over a 5-year period (2019-2023).

Main Methods:

  • Utilized the Medicare Benefits Schedule (MBS) database for incidence analysis.
  • Stratified data by sex and year, adjusting for population changes using Australian Bureau of Statistics data.

Main Results:

  • 1558 L-TDRs were performed, with a mean annual volume of 311.6 cases.
  • A downtrend and plateau in L-TDR rates were observed from 2021 onwards.
  • L-TDR was more common in males and individuals aged 35-54.

Conclusions:

  • The adoption of L-TDR in Australia has decreased over the study period.
  • Continued L-TDR use is contingent upon the availability of robust long-term outcome data.