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Clinical Characteristics of Patients with Takayasu Arteritis Undergoing Open or Endovascular Operations in China

Xihao Zhang1,2, Liang Gui1,3, Ruihao Li1,4

  • 1Department of Vascular Surgery, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, 100005 Beijing, China.

Reviews in Cardiovascular Medicine
|November 1, 2024
PubMed

Insights

Takayasu arteritis commonly affects subclavian and carotid arteries, with Type V patterns frequent. Vessel involvement significantly influences surgical intervention choices in these patients.

Area of Science:

  • Vascular Surgery
  • Cardiology
  • Rheumatology

Background:

  • Takayasu arteritis is a large vessel vasculitis with unclear operational rates and vessel involvement patterns.
  • Understanding these factors is crucial for managing patients undergoing surgical interventions.

Purpose of the Study:

  • To investigate clinical characteristics, vessel involvement, angiographic classification, and operation details in a large cohort of Takayasu arteritis patients.
  • To clarify the relationship between vessel involvement patterns and surgical management.

Main Methods:

  • A retrospective analysis of 153 consecutive patients with Takayasu arteritis undergoing open or endovascular operations.
  • Data collected included demographics, clinical presentations, vascular involvement patterns, and surgical procedures.

Main Results:

  • The majority of patients were female (83.7%), with hypertension being the most common finding (66.7%).
  • Subclavian (74.2%), carotid (70.1%), and renal (68.9%) arteries were most frequently involved. Type V angiographic pattern was most common (40.5%).
  • Renal and carotid artery involvement correlated with higher operation rates. Procedures included PTAs, stent placements, and bypass grafts.

Conclusions:

  • Subclavian and carotid arteries, along with Type V patterns, show high involvement in Takayasu arteritis patients undergoing operations.
  • Angiographic features influence clinical presentation and dictate the feasibility and type of surgical interventions.
Abstract

Keywords:
Takayasu arteritisangiography manifestationclinical characteristicssurgery

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