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Normative data of hemoglobin concentration and free erythrocyte protoporphyrin in a private pediatric practice
Clinical Pediatrics
|April 1, 1986
Insights
Elevated free erythrocyte protoporphyrin (FEP) levels, a potential indicator of iron deficiency, were found in nearly 30% of 9-month-olds. This study investigated FEP and hemoglobin in 788 children, highlighting prevalence and correlations.
Area of Science:
- Pediatric Health
- Clinical Chemistry
- Nutritional Science
Background:
- Iron deficiency is a common nutritional concern in infants and children.
- Early detection of iron status is crucial for optimal child development.
- Free erythrocyte protoporphyrin (FEP) is a biomarker linked to iron metabolism.
Purpose of the Study:
- To determine the prevalence of elevated FEP levels in a pediatric population.
- To investigate the relationship between FEP and hemoglobin concentrations in children.
- To assess FEP as a screening tool in routine pediatric check-ups.
Main Methods:
- Analysis of free erythrocyte protoporphyrin (FEP) and hemoglobin levels.
- Study conducted on 788 children during routine pediatric visits.
- Statistical analysis to identify correlations between FEP and hemoglobin.
Main Results:
- 29.8% of 9-month-old infants exhibited FEP levels above 3.0 ZPP/gm hemoglobin.
- 9.6% of the total pediatric group tested showed elevated FEP levels.
- Correlations between FEP concentrations and hemoglobin levels were observed.
Conclusions:
- Elevated FEP levels are prevalent in young children, particularly 9-month-olds.
- FEP may serve as a useful indicator for further iron status assessment in pediatric practice.
- Routine screening for FEP could aid in early identification of potential iron imbalances.
Abstract:
Free erythrocyte protoporphyrin (FEP) and hemoglobin concentrations in 788 children were investigated during routine check-ups in a private pediatric practice. FEPs greater than 3.0 ZPP/gm hemoglobin were found in 29.8 percent of 9-month-olds and in 9.6 percent of the total group tested. Correlations between FEP levels and hemoglobin concentrations are presented.