Related Experiment Video
Updated: May 8, 2026
06:18
A Bedside, Single Burr Hole Approach to Multimodality Monitoring in Severe Brain Injury
Published on: March 26, 2019
8.9K
Cerebellopontine Angle Meningiomas: A Multi-Institutional Cohort Study
Neel H Mehta1,2, Ruchit V Patel1,2, Saksham Gupta2,3
1Harvard Medical School, Boston , Massachusetts , USA.
Neurosurgery
|November 1, 2024
Summary
Gross total resection (GTR) is crucial for managing cerebellopontine angle (CPA) meningiomas, improving symptom control and reducing recurrence. Drilling the internal auditory canal (IAC) significantly aids GTR in tumors with intracanalicular invasion.
Area of Science:
- Neurosurgery
- Oncology
Background:
- Cerebellopontine angle (CPA) meningiomas pose surgical challenges due to their location near critical neurovascular structures.
- Predicting patient recovery after CPA meningioma resection remains variable, impacting clinical management and outcomes.
Purpose of the Study:
- To examine the presentation, management strategies, and patient outcomes for CPA meningiomas.
- To identify factors influencing tumor progression or recurrence after resection.
Main Methods:
- Retrospective review of 95 patients with CPA meningiomas undergoing resection.
- Descriptive statistics and logistic regression analysis to identify predictors of progression/recurrence.
Main Results:
- Hearing loss, ataxia, and headaches were the most common presenting symptoms.
- Gross total resection (GTR) was achieved in 62.1% of patients; smaller tumor size and drilling the internal auditory canal (IAC) for intracanalicular invasion predicted GTR.
- Progression/recurrence occurred in 25.3% of patients; older age and Simpson grades I/II were associated with lower recurrence odds.
Conclusions:
- Achieving GTR is essential for optimal symptom control and reducing recurrence rates in CPA meningiomas.
- Drilling the IAC is a key factor for achieving GTR in tumors with intracanalicular invasion.
