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Published on: January 31, 2020
Approaching Dynamic Behaviors of Life through Systems Chemistry
Ruirui Gu1, Kim Lambertsen Larsen2, Ali Wang3
1Key Laboratory for Advanced Materials, Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, Frontiers Science Center for Materiobiology and Dynamic Chemistry, School of Chemistry and Molecular Engineering, Institute of Fine Chemicals, East China University of Science and Technology, 130 Meilong Road, Shanghai, China.
Abstract:
The intricate interplay of metabolic reactions and molecular assembly in living systems enables spatiotemporally organization and gives rise to diverse dynamic behaviors that characterize life. Over the last decades, research efforts have increasingly focused on replicating the remarkable properties and characteristics of living systems, driving the rapid growth of systems chemistry. This young discipline which generally studies interacting molecular networks and emergent system-level properties, behaviors, and functions, offers new concepts and tools to tackle the complexity of life. In this review paper, we have explored seminal research and recent advancements in recreating dynamic behaviors of life with systems chemistry. We believe that the recreation of the dynamic behaviors of life through systems chemistry would set the initial steps to obtain synthetic life de novo.
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